RNA METHYLTRANSFERASE NSUN2-MEDIATED M5C METHYLATION PROMOTES CR(VI)-INDUCED MALIGNANT TRANSFORMATION AND LUNG CANCER BY ACCELERATING METABOLISM REPROGRAMMING

RNA methyltransferase NSUN2-mediated m5C methylation promotes Cr(VI)-induced malignant transformation and lung cancer by accelerating metabolism reprogramming

Hexavalent chromium [Cr(VI)], one common environmental contaminant, has long been recognized as a carcinogen associated Fishing Gear with lung cancer, but roles and mechanisms of Cr(VI)-induced epigenetic dysregulations in carcinogenesis remain to be investigated.In this study, we identified that RNA m5C methyltransferase NSUN2 was significantly up

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Examining the Effect of Capital Structure and Financing on the Technical Efficiency of Pharmaceutical Companies Listed on the Stock Exchange

Introduction: Choosing an optimal capital structure is prerequisite for maximizing the firm value.Given the competitive market conditions, determining the appropriate method of financing companies is boost for increasing their efficiency and viability.Methods: This paper is composed of two main sections: the first section examines the relationship

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